Difference between prototype and Ajax implementation under jquery

Let’s first list the implementation of Ajax in Jquery and prototype.
Jquery：

Copy the codeThe code is as follows:

 
<script language="javascript"> 
$(function(){ 
var box = {}; 
var remoteUrl = ''; 
= 5*60*1000;//5 minutes
 = function() { 
(remoteUrl, function(data){ 
var msg_box = $('#msg_box'); 
msg_box.innerHTML = data; 
} 
}); 
} 
 = function(){ 
(); 
setInterval(,); 
}; 
(); 
}) 
</script> 

prototype:

Copy the codeThe code is as follows:

 
<script language="javascript"> 
var box = {}; 
= 5*60*1000;//5 minutes
 = function(){ 
var pars = ""; 
var remoteUrl = ''; 
var myAjax = new ( 
remoteUrl, 
{ 
method: 'get', 
parameters: pars, 
onComplete:  
}); 
}; 
 = function(data){ 
var msg_box = $("msg_box") ; 
msg_box.innerHTML = ; 
}; 
 = function(){ 
(); 
setInterval(,); 
}; 
(); 
</script> 

In fact, the prototype cannot be refreshed after introducing the setInterval function. Why is this?
It turns out that prototype has a cache mechanism for the same URL, so the page should not be refreshed. Especially after the user uses F5 or clicks "Refresh", a blank bug will appear in the Ajax response area, so the prototype must not be refreshed.
Add a random number for URLs in prototype
Original: var remoteUrl = '';
After modification: var remoteUrl = '?rand='+();
Use the GET method to generate a parameter that is not related to the page display.